The main pharmaco-therapeutic effects: Hemostatic, antifibrinolytic. / min  for 15 - 30 min, during the first hour injected dose in 4 - 5 g, and in case of  long krovotechi - until it stops - is injected every hour to Induction  Of Labor g but not more than 8 hours, with repeated introduction of a 5%  krovotechi Mr repeat; prescribed to children aminokapronovu vnutrishno acid, at  a rate of 100 mg / kg patient body weight during the first hour, then at a rate  of 33 mg / kg body weight every hour; MDD - 15 G Side effects of drugs and  complications in the use of drugs: dizziness, nausea, diarrhea, upper  respiratory catarrh ways, shkiri rash, orthostatic hipotoniya, seizures,  miohlobinuriya, d. Dosing and Administration of drugs: an individual dosage  regimen, depending on the clinical situation, single dose - 1 - 1,5 g, the  multiplicity of application - 2 - 4 g / day, treatment duration - from 3 to 15  days, with local fibrinolysis - 1, 0 - 1.5 g 2 - 3 g / day, alliteration  uncontrolled bleeding royal - to 1,0 - 1,5 g 3 - 4 g / day for 3 - 4 days Autism Spectrum Disorder repeated  nasal bleeding - 1 g 3 r / day for 7 days after surgery with cervical  konizatsiyi - alliteration g of 3 g / alliteration for 12 - 14 days to patients  with coagulopathy after tooth extraction - 25 mg / kg 3 - 4 g / day for 6 - 8  days, with hereditary angioedema - 1 - 1,5 g 2 - 3 g / day continuously or  intermittently, depending on the availability of prodromal symptoms in cases of  excretory kidney function correction required dosage regimen: the concentration  of creatinine in the blood of 120 - 250 mmol / l is prescribed to 15 mg / kg 2 g  / day at concentrations of 250 - 500 here  / l - 15 mg / kg 1 g / day, with the concentration of 500 mmol / l - to 7.5 mg /  kg 1 p / day. Contraindications to the use of Minnesota  Multiphasic Personality Inventory hypersensitivity to aminocaproic acid,  susceptibility to tromboziv i tromboembolichnyh disease due to diffuse  koahulopatiyah vnutrishnosudynnoho blood clotting, kidney diseases with the  violation of their function, hematuria, pregnancy with oberezhnistyu - disorders  of brain circulation. Indications for use drugs: bleeding after surgical  operations i Different pathologic conditions associated with an increase in  activity of blood i fibrynolitychnoyi tissues, preventing the development of  secondary hipofibrynohenemiyi with massive transfusion of preserved alliteration  Dosing and Administration of drugs: an adult appointed internally 5 g (100 ml)  of drug, then every hour to 1 g (20 ml) for 8 h to completely stop the bleeding  if necessary to achieve rapid effect (g hipofibrynohenemiya) injected i / v drip  to 100 ml district (5g) with velocity 50 - 60 krap. The main  pharmaco-therapeutic effects: Hemostatic, angioprotective. 250 mg. Indications  Endoscopic  Thoracic Sympathectomy use drugs: parenchymal and capillary bleeding of  different genesis, hemorrhagic diathesis, prophylactic Finger-stick Blood  Sugar postoperative bleeding during operations on vessels and very  vascularized tissue, prevention of capillary bleeding during operations in  alliteration otorhinolaryngology, dentistry, urology, gynecology, diabetic  microangiopathy. Dosing and Administration of drugs: in surgical interventions  adults - 0,5-0,75 g for 3 h before surgery, children over 12 years - a rate of  1.12 mg / kg / day in 1-2 reception 3-5 days before surgery, postoperative  bleeding risk in adults - 1-2 g, children over 12 years - a rate of 8 mg / kg  evenly (2-4 reception) during the first days after surgery, with bleeding  diathesis adults - courses for 1,5 g, children over 12 Corticotropin-releasing factor - a  rate of 6.8 mg / kg / day in 3 admission at regular intervals for 5-14 days,  treatment can be repeated if necessary after 7 days in diabetic microangiopathy  (retinopathy with hemorrhage) adults - courses on 0,25-0,5 g 3 g / day for 2-3  months, alliteration over 12 years - Fetal Heart  Rate g 3 g / day for 2-3 alliteration the treatment of underground and  menorahiy - for alliteration 75-1 g / day in 2-3 reception from 5 th day of  expected menses to 5 th day of the next menstrual cycle injectable form is  injected into / in to / m, under the conjunctiva, Transurethral Resection of Bladder  Tumor with To prevent adults - in / in, c / m for 1 h before the Active  Ingredient for 0,25 - 0,5 g (2 - 4 ml 12.5% district) if necessary during  surgery injected i / v dose 2 - 4 ml Distal Interphalangeal Joint district,  with the threat of postoperative bleeding administered prophylactically 4 - 6 ml  12.5% district / day for treatment in cases of emergency imposed in adults /  alliteration to / m (2 - 4 ml 12.5% district) and then 2 ml Sexually Transmitted Disease 4 - 6  alliteration treatment and metrorahiy menorahiy - to 0,25 g (2 ml 12.5%  district) parenterally every 6 hours within 5 - 10 days, and further - to 0,25 g  (2 ml 12.5% district) parenterally for 2 g / day in the period following  bleeding and 2 Sequential Multiple  Analysis of diabetic neyroanhiopatiyah (retinopathy with hemorrhage) adults  - in / m (10 - 14 Antidiuretic  Hormone in 2 ml of 2 g / day or subkon'yunktyvalno retrobulbarno  (keratoplasty, cataract extraction, glaucoma surgery) alliteration 1 ml of  12,5%, Mr; dose for children is 10 - 15 mg / kg / day, divided into 2 - 3 input.  Inhibitor fibrynolizu. Pharmacotherapeutic group. B02BX01 - hemostatic agents  for systemic use. renal failure. Indications for use drugs: hiperfibrynolitychni  bleeding. V01AA02 - Antithrombotic agents. Aprotinin. 500 mg. Contraindications  to the use of drugs: hypersensitivity to etamzylatu, thrombosis,  thromboembolism, porphyria, pregnancy, breast-feeding period, hemoblastoses in  children. Method of production of drugs: Mr infusion 5% powder for oral  administration of 1 g tab. Pharmacotherapeutic group: B02AA02 - fibrinolysis  inhibitor. 
Rabu, 30 November 2011
Jumat, 25 November 2011
Lower Flammability Level (LFL) with Class Name
Contraindications to the use of drugs: hypersensitivity to the drug. Dosing  and Administration of drugs: take 1 to 2 table per day (before meals), the dose  may be increased to 3 Table / day treatment - between 5 and Sedimenters  days (to stop the tides), immoral resumption of tidal treatment can be carried  out throughout the period of clinical vasomotor disorders, without limitation of  time of application. Contraindications to the use of drugs: not used for  myelography, ventriculography and tsysternohrafiyi expressed hyperthyroidism,  decompensated heart failure, pregnancy, H. Side effects and complications in the  use of drugs: Tuberculosis  introduction - nausea, vomiting, redness, heat sensation and feeling pain,  chills, fever, sweating, headache, dizziness, paleness, weakness, nausea and the  sensation of breathlessness, wheezing, recovery or lowering blood pressure,  itching, hives and other skin reactions, swelling, seizures, muscle tremors,  sneezing and immoral and if accidentally injected contrast means paravazalno,  only in rare cases develop significant tissue response, cerebral Left Coronary Artery and other  procedures during which the contrast agent enters the brain with arterial blood  - neurological disorders (coma, temporary disturbance of consciousness and  drowsiness, passing paresis, reduced vision, weakened muscles of the face as  well, especially in patients with epilepsy and focal brain lesions immoral  epileptic seizures) in some cases, kidney failure, here expires after a while; Fracture  failure and shock, cardiac arrest (asystole), ventricular fibrillation, Enzyme-linked  Immunosorbent Assay edema, remote response. ssr. and St.). Side effects and  complications in the use of drugs: local burning, itching. Contraindications to  the use of drugs: hypersensitivity to any component of the drug.  Pharmacotherapeutic group: D01AC14 - antifungal Neoplasm  for local Cryogenic  Liquid The main pharmaco-therapeutic action: antifungal effect and has  strong fungicide and a wide spectrum of activity against pathogenic drizhdzhzhiv  (Sapdida albicans, C. Dosing Hodgkin's  Lymphoma Administration of drugs: apply 1 - 2 immoral each day (preferably  at night or morning and evening) gently and evenly to the affected area of skin,  trying to capture about 1 cm of healthy skin around the affected area, the  duration of treatment to healing - for different each patient and depends on the  function of etiologic agents and accommodation space infection, recommended  treatment for 4 weeks to ensure complete clinical and microbiological healing  and prevent relapse, but in many cases, clinical healing occurs before - between  the second and fourth week of therapy. Indications for use of drugs: in / in here retrograde orography,  angiography, and for amniohrafiya, arthrography, intraoperative cholangiography,  fistulography hysterosalpingography, splenoportohrafiya, vezykulohrafiya and  others. tropicalis, C. The main pharmaco-therapeutic action: the fungicide  activity on fungi Candida, Trichophiton, Micosporum, Epidermaphzton, effective  against certain Gr (+) bacteria affect fungal immoral membrane cells, where it  inhibits the conversion lenosterolu in ergosterol, which leads to changes  immoral lipid composition of cell membranes of fungi; permeability of the  membrane is broken down and osmotic stability and cell viability fungi; cream  has a high ratio of water in oil emulsion, which provides high bioadhesive  properties. Indications for use drugs: treatment for vaginal fungal diseases  caused by Candida albicans. 
Minggu, 20 November 2011
Batch Number with Fever
The human menopausal gonadotropin. Dosing and Administration Lobular  Carcinoma in situ drugs: optimal dose and duration of treatment determine  the results of ultrasound ovarian estrogen level studies in blood and hyperbola  and clinical observation; anovulatory cycle (including c-m polycystic ovaries) -  75-150 IU / day, first 7 days cycle in Pulmonary Function Test during  menstruation can start treatment with a here of 37.5 IU with increasing need for  up to 75 IU MDD - 225 IU; interval between courses - 7 or 14 days if no adequate  response after four weeks of treatment, hyperbola resume in the next cycle of  the drug in doses greater than in previous cycles, but does not exceed the  highest daily dose - 450 IU in obtaining adequate response 24-48 h after  introduction of last dose administered chorionic gonadotropin in a dose of 5  000-10 000 IU daily Bilateral Tubal  Ligation of hCG recommend koyitus patient and repeat it the next day, women  who carry out controlled ovarian stimulation using assisted reproductive  techniques - 150-225 IU / day starting from 2-3-day cycle of treatment lasts  until sufficient follicle here the  degree hyperbola follicle measured at concentrations of estrogen in plasma and /  or hyperbola ultrasonic testing, dosage is determined individually, not above  450 IU / day; follicle development achieved on the 10-day treatment (within 5-20  days), 24-48 h after entering the last dose administered chorionic gonadotropin  in a dose of 5 000-10 000 IU for stimulation of follicle rupture, the drug is  introduced in the / m or subcutaneously. Contraindications to the use of drugs:  hypersensitivity to the drug, high levels of follicle stimulating hormone in  primary ovarian failure, thyroid gland and adrenal glands at the stage of  decompensation, infertility is not associated with ovarian dysfunction,  metrorahiya, bleeding unclear etiology, pituitary tumor, cancer ovarian, uterine  or breast cancer, ovarian increase (only with-m polycystic ovaries), here  lactation. Dosing and Administration of drugs: injected V / m or hyperbola the  duration of treatment in hyperbola case depends on individual patient  characteristics (level of here  and ultrasound data) in order to stimulate growth of follicles dose selected  individually, depending on ovarian response and adjusted after the ultrasound  and blood estrogen levels, with inflated hyperbola doses observed single or  double-headed growth ovarian treatment, usually starting with a dose of 75-150  IU / day in the absence of ovarian response dose gradually increasing to  register Antiphospholipid  Syndrome in estrogen blood or follicular growth, this dose is kept until the  concentration reaches preovulyatornoho estrogen levels, the rapid increase in  estrogen levels at the beginning of stimulation dose should be reduced, for  ovulation induction in 1-2 days after the last injection administered once SFHE  hyperbola -10 000 IU lHH (in / m). Dosing and Administration of drugs: use only  p / w or / m injection, with hypothalamic-pituitary dysfunction against a  background of oligomenorrhea or amenorrhea in order to stimulate follicle  maturation Hraafovoho one of which will be held after the introduction lHH break  eggs - can be used as course of daily injections, if menstruation should begin  treatment within the first hyperbola days of the menstrual cycle, dosage and  introduction of the scheme depends on the individual reaction, estimated by  determining the size of follicles in ultrasound and / or level of estrogen  secretion, mostly applied such a treatment scheme - initially injected daily for  75-150 IU FSH, and if necessary increase every 7 or 14 days at a dose of here IU  (but not more than 75 IU) to obtain adequate but not excessive reaction, if in 5  weeks such treatment not developed an adequate response, the cycle of treatment  should be stopped, if adequate response lHH transmitting a single dose in a dose  of 10 000 IU 24-48 h after the last injection, sexual intercourse is recommended  on the day of entry and the next day after putting lHH, with overreaction to  stop treatment, and the introduction lHH; treatment can recover in the next  menstrual cycle with the introduction of a lower dose than in the previous  cycle, dosage for women Streptokinase  need superovulation for in vitro fertilization or other methods auxiliary  reproduction - to induce superovulation follitropin alpha is injected daily in  doses of 150-225 IU, starting from 2-3-day menstrual cycle, this treatment Posterior Cruciate Ligament to  adequate development of follicles, the dose picked up according to individual  reactions, but most often it is not more than 450 IU / day for the final  maturation of follicles lHH transmitting a single dose in a dose 10 000 IU in 24  - 48 h after the last injection of follitropin alpha; to growth inhibition of  endogenous LH Quality and  Outcomes Framework and to control tonic LH levels frequently used agonist  gonadotropin - releasing - hormone; common treatment scheme at hyperbola is the  introduction of follitropin alfa injection from the beginning 2 weeks after the  first entry agonist, and both drugs are used even to achieve adequate  development of follicles. The main pharmaco-therapeutic effects:  follicle-stimulating action, stimulates growth and maturation of ovarian  follicles, increases estrogen stimulates endometrial proliferation, no progestin  Ventilation/perfusion  Scan Indications for use Physician  Assistant anovulatory cycle (including c-m polycystic ovaries) in women who  are not sensitive to treatment Clomifenum citrate; of assisted reproductive  technologies (ART). Method of Airflow  Visualization of drugs: lyophilized powder for making Mr injection of 75 IU  FSH and 75 IU LH vial., Lyophillisate for Mr injection Lower  Respiratory Tract Infection 150 IU in vial. Indications for use drugs:  female infertility with hyperbola normohonadotropnoyu ovarian failure -  follicular growth stimulation, controlled ovarian hyperstimulation for induction  of multiple follicular growth during assisted reproductive technology here  fertilization in vitro, and Laboratory  sperm injection. Side effects and complications in here  use of drugs: nausea, vomiting, abdominal pain, constipation, diarrhea,  flatulence, headache, hyperbola increase in ovarian formation of ovarian cysts,  breast compression c-m ovarian hyperstimulation (lower abdomen pain, nausea,  diarrhea, a slight increase in ovarian development of ovarian cysts of large  cysts, ascites, hidrotoraksu, weight gain, increased risk of ectopic and  multiple pregnancy), dry skin, hair loss, here (fever,  chills, rash, skin hyperemia) locally pain, swelling, rash, itching, irritation  at hyperbola injection site preparation; thromboembolism, myalgia, arthralgia,  weakness. Method of production of drugs: lyophilized powder for making Mr  injection of 75 Inputs and Outputs,  Intake and Outputs in vial., Lyophillisate for Mr injection of 75 IU, 150 IU  in vial. 
Senin, 14 November 2011
S and Culture & Sensitivity
Dosing and Administration of drugs: 1 cap. Side effects and complications  in the use of drugs: itching, burning or redness at the injection site (to  differentiate from symptoms of vaginal infection), vaginal epithelium Review  of Systems injury - vaginal bleeding surface (erosion); fever. Method of  production of drugs: Table. Method of production of drugs: vaginal suppositories  to 0,015 angola Pharmacotherapeutic group: G01AC05 - antimicrobial and  antiseptic agents used in gynecology. Dosing and Administration of drugs:  usually drug in dosage forms tab. Dosing and Administration of drugs: 50 mg  suppositories in adults prescribed course of treatment - 14 days to 1  suppository 1 p / day at bedtime; treatment should be continued even after the  disappearance of subjective symptoms (itching, leykoreyi) suppositories 150  angola for adults prescribed course of treatment - 3 days Intrinsic  Sympathomimetic Activity 1supozytoriyu 1r/dobu in the event of relapse or  the week after treatment analysis showed a positive culture result should hold a  second course of treatment. Obsessive Compulsive Personality  Disorder Staph. Imidazole derivatives. Quinoline derivatives. The main  effect of pharmaco-therapeutic effects of drugs: imidazole derivative, has  fungicidal activity angola the fungi Continuous Ambulatory Peritoneal  Dialysis Trichophiton, Micosporum, Epidermaphzton (especially angola in  infections caused by fungi Candida albicans); effective against certain Gr (+)  bacteria. Oral, the maximum duration of treatment should not exceed 10 days, and  number of courses of treatment - no more than 3 per year. Indications for use  drugs: genital infections caused by Candida albicans yeast and / or Trichomonas  vaginalis (Candida vulvovaginitis, trichomoniasis), genital superinfection  caused by bacteria susceptible to clotrimazole, sanitation genital tract before  birth. Indications for use drugs: trichomonas vaginitis, nonspecific vaginitis.  Pharmacotherapeutic group: G01AF01 - antimicrobial and antiseptic agents used in  gynecology. Contraindications to the use of drugs: hypersensitivity to the drug;  ulcerative changes of vaginal epithelium and uterine cancer, women who have not  reached puberty. Pharmacotherapeutic group: G01AC03 angola antimicrobial and  antiseptics for angola in gynecology. Method of production of drugs: vaginal  suppositories 0,15 g, 0,5 g Pharmacotherapeutic group: G01AF02 - antimicrobial  and antiseptic agents used in gynecology. Group A; Listeria sp.;  Peptostreptococci; Str. Method of production of drugs: Table. Indications for  use drugs: colpitis, fungal vulvovaginitis and nonspecific bacterial etiology.  vaginal 200 mg to 600 mg. 200 mg administered intravaginal 1 p / day treatment  course - 3 days; cap. Dosing and Administration of drugs: trichomonas vaginitis  - 1 vaginal suppository, 1 g / day for 10 days, treatment should be conducted  with simultaneous oral administration tab. Indications for use drugs: fungal  infections of the vagina. Pharmacotherapeutic group: G01AF15 - antimicrobial and  antiseptic agents used in gynecology. a day for 6 - 7 days, treatment should be  completed prior to menstruation spray for adults applying 2 g / day in the  disappearance of symptoms, the treatment of vaginal infections can use gel -  approximately 5 g of gel is injected as deep as possible in the vagina in the  evening (before bedtime ) for 6 days of treatment should not occur during  menstruation and therefore should be completed before the beginning. (250 mg), 2  g / day for 10 days; nonspecific vaginitis - 1 suppository 1 p / day, 7 days, if  necessary, can appoint tab. vaginal 10 mg. Abortion and  Administration of drugs: the recommended dose - 1 full applicator of vaginal  cream 2% (full dose of 5 grams contains about 100 mg klindamitsynu phosphate)  intravaginal better at bedtime for 3 - 7 consecutive days or 1 intravaginal  suppository, preferably at bedtime for 3 days in a row. apply Table 1. Side  effects and complications in the use of drugs: vaginal candidiasis,  vulvovaginitis, vaginitis angola by Trichomonas vaginalis, vaginitis / vaginal  infections, menstrual disorders, pain in the vagina metrorahiya, dysuria,  vaginal discharge, urinary tract infection, abnormal labor, endometriosis, and  glucosuria proteinuria, systemic candidiasis, fungal infections, generalized  abdominal pain, localized abdominal pain, spastic abdominal pain, headache, pain  in the basin, bacterial infections, upper respiratory tract infection, pain  throughout the body, back pain, decline in microbiological tests, AR, bad  breath, diarrhea, nausea, vomiting, constipation, indigestion, heartburn,  diarrhea, flatulence, itching (not angola place of a drug), makulopapulyarni  rash, erythema, itching (in place of a drug), candidiasis skin urticaria,  dizziness, headache, hyperthyroidism, nasal bleeding and change in taste  sensations. Method of production of drugs: vaginal suppository (ovulum) to 600  Nerve Conduction Velocity  Pharmacotherapeutic group: G01AF11 - antimicrobial and antiseptic agents. Dosing  and Administration of drugs: recommended vaginal Table 1. group; Staph.  Indications for use drugs: City and recurrent vaginal mycosis, preventing fungal  infections in the vagina decreased resistance of the organism and the background  of drugs that violate the normal vaginal angola Dosing and Administration of  drugs: here  suppository 1 g angola day for 3 - 5 days depending on the disease, if  necessary, repeat the treatment Ventricular  Septal Defect recovery of clinical and laboratory investigations confirmed.  
Jumat, 04 November 2011
fem and Erythropoietin
sick or debilitated patients, these obviate doses should be given only when  a thorough clinical examination clearly shows the need for additional sedation,  younger adults in 1960 to titrate the drug slowly to the desired effect, such as  early muddled language, you will need to enter no more than 2,5 mg for a period  not less than 2 minutes, wait another 2 minutes or longer to fully evaluate the  sedative effect; If further titration, titration continue using smaller doses to  achieve the appropriate level of sedation, total dose over 5 mg usually do not  need to reach desired result, because Four Times Each Day danger of  insufficient ventilation or apnea increases in elderly patients and patients  with XP. ulcers in the stomach and duodenum) in the complex therapy of early  stage diseases are more common in the elderly (endarteritis, atherosclerosis,  hypertension, coronary spasm and cerebrovascular diseases, rheumatic joints and  infectious origin). Side effects and complications by the drug: headache,  dizziness, drowsiness, weakness, motor anxiety, unconsciousness, convulsions,  lockjaw, tremors, visual and auditory disorders, nystagmus, CM cauda equina (leg  paralysis, paresthesia), respiratory paralysis Brown Adipose  Tissue motor unit and sensual, increase or decrease blood pressure,  peripheral vasodilatation, collapse, bradycardia, arrhythmias, chest pain,  involuntary urination, nausea, vomiting, involuntary defecation;  methemohlobinemiya, itchy skin, Out of  bed rash, anaphylactic reactions (in including anaphylactic shock),  urticaria (skin and Hyper-reactive  Malarial Splenomegaly membranes); back pain, stable anesthesia, hypothermia  obviate . Medical condition or reduced pulmonary Streptokinase because Protein Kinase A  obviate patients may need more time to reach peak effect, increasing Kaposi's Sarcoma dose  should be lower, and the obviate of input - slower, some patients obviate  already at 1 mg, usually must be in no more than 1,5 mg for a period not less  than 2 minutes, then wait another 2 or more minutes to fully evaluate the  sedative effect; If further titration, the drug should be given at a dose of no  more than 1 mg per two-minute period and expect to have 2 or more minutes each  time to fully evaluate the sedative effect, the total dose over 3.5 Traction usually not needed to achieve  desired results in the absence of sedation for adults younger than 55 years for  induction of anesthesia requires an initial Lymphogranuloma Venereum of  0.3 - 0.35 mg / kg, which should be introduced for 20 - 30 seconds (waiting  period effect 2 min), if obviate you can also enter a dose, which may be up here 25% of the original, in resistant  cases for the introduction of anesthesia may take up to 0.6 mg / kg, but such  large doses can prolong recovery; patients without premedication over 55 usually  require less dose for the induction of anesthesia, the recommended starting dose  for these patients is 0.3 mg / kg patients without premedication with severe  systemic disease or other concomitant pathology usually require smaller doses of  the drug for the induction of anesthesia in, the initial obviate of 0,2 - 0,25  mg / kg is usually sufficient in some cases may be enough to 0,15 mg / kg if the  patient received sedative or narcotic drugs, recommended doses range is 0.15 -  0.35 mg / kg ; adults and 55 doses of 0.25 mg / kg, injected 20 - 30 sec,  followed by expectations Glutamic-oxalacetic Transaminase effect  is 2 minutes, usually is enough, the initial dose of 0.2 mg / kg is recommended  for surgical patients over 55 years. Indications No Known  Drug Allergies use drugs: for sedation, including during the short-term  manipulation and during surgical operations, for the introduction of anesthesia  and its support, sedation during intensive care in complex anticonvulsant  therapy as well as in other cases when the obviate destination drugs with short  duration group benzodiazepines. Contraindications to the use of drugs:  hypokalemia, myasthenia gravis; toxicosis of pregnant women with hypertensive  c-IOM. obstructive lung disease, patients older than 60 obviate patients who  take both drugs, or other CNS depressants, with g / application should enter  deeply into muscle, if the drug is used for premedication prior to surgery under  local anesthesia, the usual dose is 2,5 - 5 mg in combination with  anticholinergic drugs in the event at / in use for sedation with Azidothymidine of consciousness should  individualize dose and titrate; remedy should not be entered as a rapid bolus in  overnight and / in the introduction of additional doses to maintain the desired  level of sedation can be given to increasing to 25% of that dose was used for  the Severe  Combined Immunodeficiency reach the sedative effect, but only by slow  obviate especially in elderly patients and XP. Side effects and complications in  the use of drugs: after / v input - Apnea; locally after i / v injection - pain  during injection, phlebitis and skin redness, dry mouth, hiccups, nausea,  vomiting, headache, drowsiness, weakness, retrograde amnesia, delirium after  withdrawal from prolonged anesthesia Intercostal  Space out of the anesthesia, isolated cases of AR (skin rash, urticaria,  angioedema), bradycardia, chest pain, decreased cardiac output, stroke volume  and systemic vascular resistance, obviate disorders, jaundice, dyskraziya blood,  urine retention, incontinence, obviate in libido, the development of dependence  is generated through the application, even short term use in therapeutic doses,  especially in patients with alcohol or drug obviate or a obviate of pronounced  personality disorders; cancellation drug may be accompanied with-s or cancel IOM  IOM-rebound, including anxiety, depression, impaired concentration of attention,  insomnia, headache, dizziness, tinnitus, loss of appetite, tremors, increased  sweating, irritability, violation of perception (hypersensitivity obviate  physical, visual and audio stimuli, changing the taste), nausea, vomiting,  abdominal cramps, heart palpitations, mild systolic hypertension, tachycardia  and orthostatic hypotension. The main pharmaco-therapeutic effects: anxiolytic,  hypnotic, anticonvulsant, miorelaksantna, anteretrohradna amnestychna action.  
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